Mechanism of Action

CoQ10, due to its involvement in ATP synthesis, affects the function of all cells in the body, making it essential for the health of all-human tissues and organs. CoQ10 particularly affects the cells that are the most metabolically active

Clinical Indications:

Immune Function - enhances phagocytic activity of macrophages and increases granulocyte proliferation. 3-5 Its antioxidant activity helps prevent AIDS- related diseases caused by oxidative stress.6 Blood levels of CoQ10 are lower in AIDS patients and 200 mg/day increased T-helper/suppresser ratios.

Muscular Dystrophy - CoQ10 deficiency is found in cardiac and skeletal muscle in animals and humans with hereditary muscular dystrophy.

Diabetes Mellitus - The electron-transport chain is integrally involved in carbohydrate metabolism. CoQ7 at a daily dose of 120 mg for 2-18 weeks reduced fasting blood sugar by at least 30% in 31% of patients.

Cancer - prevents metastasis and enhances remission in breast cancer. 8,9 Mechanisms in cancer include immune system enhancement and antioxidant activity.

Allergy - inhibits release of histamine and SRSA in antigen-challenged animals.

Periodontal Disease - Gingival biopsies yield subnormal tissue levels of CoQ10 in patients with periodontal disease. 10-13 Supplementation speeds healing after periodontal surgery.

Male Infertility - CoQ7 (CoQ10 analog) at 10 mg/day resulted in significant increases in sperm count and motility.